Sunday, November 27, 2011

More research on Serotonin, Depression and Scleroderma

Commonly Used Antidepressants May Also Affect Human Immune System 2006

Depression may involve autoimmune attack on serotonin (5-HT) Dec 2011

"The incidence of anti-5-HT antibody activity was significantly higher in depressed patients (54.1%), and in particular in those with melancholia (82.9%), than in controls (5.7%)."

Biogenic amines derived from tryptophan in systemic and cutaneous scleroderma.

"An increased T/IAA ratio seems to be of prognostic significance in scleroderma, suggesting an adverse course of the disease."

NeuroScience - Offers Urine Test for 5HT levels

How to lower serotonin levels naturally... (Livestrong)

Effect of antibiotics on D-serotonin-reactive structures

Balancing gut flora and the "second brain" without prescription medication

Cardiac fibrosis and Serotonin

Tryptophan Depletion and Mood Disorders

Tryptophan, serotonin, and aging This man is a genius (Ray Peat)

Increased brain serotonin turnover in panic disorder patients in the absence of a panic attack: Reduction by a selective serotonin reuptake inhibitor

Neurogenesis and Serotonin

Too much not too little serotonin may trigger depression

The Other Brain Also Deals With Many Woes
Published: October 11, 2011

Serotonin Findings Cause Depression Rethink

Serotonin Syndrome

Think Twice: How the Gut's "Second Brain" Influences Mood and Well-Being

Serotonin and Gut/Esophageal Peristalsis (Important to Scleroderma Patients)
The effect of erythromycin on human esophageal motility is mediated by serotonin receptors.

Acute autoimmune encephalomyelitis in mice. II. Susceptibility is controlled by the combination of H-2 and histamine sensitization genes.

Compounds that induce autoimmunity in the Brown Norway rat sensitize mast cells for mediator release and interleukin-4 expression
David B. G. Oliveira1,*, Kathleen Gillespie1, Karen Wolfreys1, Peter W. Mathieson1, Faieza Qasim1, John W. Coleman2

Elevated Serotonin Levels in Autism: Association with the Major Histocompatibility Complex
Article first published online: 23 NOV 2005

Inhibition of Hypoglycemia-Induced Cortisol Secretion by the Serotonin Antagonist Cyproheptadine

Effect of the Serotonin Precursor, Tryptophan, on Pituitary Hormone Secretion
These effects are presumably mediated by conversion of tryptophan to serotonin within the central nervous system and suggest that serotonin is a potent inhibitor of hypothalamic CRF elaboration in man.

Effects of Selective Serotonin Reuptake Inhibitors on Thyroid Function in Depressed Patients with Primary Hypothyroidism or Normal Thyroid Function
Gisah Amaral de Carvalho, Saint-Clair Bahls, Anke Boeving, and Hans Graf. Thyroid. July 2009, 19(7): 691-697. doi:10.1089/thy.2008.0261.

Serotonin and its precursors as modulators of the immunological responsiveness in mice.

Association of erythromelalgia and Raynaud's disease responding to a serotonin reuptake inhibitor
1999, Vol. 10, No. 2 , Pages 141-144

Scleroderma treatment differs between experts and general rheumatologists
Janet E. Pope, Janine M. Ouimet, Adriana Krizova
"Erectile dysfunction (25–30) and depression (31–35) seem to be frequent problems in scleroderma, each with a substantial impact on patients, and this has been reported in the literature." = excess serotonin!!!

Selective serotonin reuptake inhibitor suppression of HIV infectivity and replication.
Psychosom Med. 2010 Nov;72(9):925-32. Epub 2010 Oct 14.

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